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BIO-322 GCU Midterm Exam 2025 Questions and Answers 6 Causes of Disease - ....ANSWER☑️☑️...--heredity (chromosomal) -trauma -inflammation (infection) -hyperplasia (neoplasms: benign vs. malignant) -nutritional imbalances (obesity/malnutrition) -immunity (allergy) Atrophy - ....ANSWER☑️☑️...-decrease in cell size Hypertrophy - ....ANSWER☑️☑️...-increase in cell size Hyperplasia - ....ANSWER☑️☑️...-increase in cell number Metaplasia - ....ANSWER☑️☑️...-reversible replacement of 1 cell type by another (like smokers) Dysplasia - ....ANSWER☑️☑️...-abnormal changes in size, shape & organization of matured cell Necrosis - ....ANSWER☑️☑️...-evoked by non-physical events (disease) -Coagulative: denature of proteins from gel to firm state (kidneys) -Liquefactive: cells digested by own hydrolases- tissue becomes soft, walled off from healthy tissue (neurons/glial cells in brain) -Caseous (cheese-like): cells disintegrate & debris is walled off -Fat: caused by lipases (breast, pancreas, abdominal) 1